Potassium Cation → Methyl 5-methyl-4-(1-methyl-4-prop-1-enylpyrazol-5-yl)thiophene-2-carboxylate

HRID 2322468Notes

Reaction equation

HRID 2322468 reaction equation
[Br:1][c:2]1[cH:3][n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][c:9]([C:13](=[O:14])[O:15][CH3:16])[s:10][c:11]1[CH3:12].[C:18](=[O:19])([O-:20])[O-:21].[CH2:30]1[O:31][CH2:32][CH2:33][O:34][CH2:35]1.[CH:24](=[CH:25][CH3:26])[B:27]([OH:28])[OH:29].[K+:22].[K+:23].[OH2:36]>>[c:2]1([CH:24]=[CH:25][CH3:26])[cH:3][n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][c:9]([C:13](=[O:14])[O:15][CH3:16])[s:10][c:11]1[CH3:12]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 236540cis-Propenylboronic acidHCID 57826393methyl 4-(4-bromo-1-methyl-1H-pyrazol-5-yl)-5-methyl-2-thiophenecarboxylate

Product 1

HCID 67066132Methyl 5-methyl-4-(1-methyl-4-prop-1-enylpyrazol-5-yl)thiophene-2-carboxylate

Sources & evidence

ORD record
ord-66a3b142b89a4fdc92c40375d157737f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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