7-Benzyl-1-bromo-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester → 7-Benzyl-1-cyano-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:23])[c:8]2[cH:9][c:10]([CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:11][cH:12][c:13]2[c:14]1[OH:15].[Cu:24][C:25]#[N:26]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([C:25]#[N:26])[c:8]2[cH:9][c:10]([CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:11][cH:12][c:13]2[c:14]1[OH:15]Participants
3
Sources & evidence
- ORD record
- ord-4d6711126b404ffab6aec4b53ac86c57
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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