4-Fluoroaniline → 5-Cyclopropyl-2-{4-[(4-fluorophenyl)amino]phenyl}-6-[(3-hydroxypropyl)(methylsulfonyl)amino]-N-methyl-2H-indazole-3-carboxamide
Reaction equation
[Br:40][c:41]1[cH:42][cH:43][c:44](-[n:45]2[c:46]([C:47]([NH:48][CH3:49])=[O:50])[c:51]3[c:52]([cH:53][c:54]([N:55]([CH2:56][CH2:57][CH2:58][OH:59])[S:60]([CH3:61])(=[O:62])=[O:63])[c:64]([CH:65]4[CH2:66][CH2:67]4)[cH:68]3)[n:69]2)[cH:70][cH:71]1.[CH:1]1([c:4]2[cH:5][c:6]3[c:7]([C:36](=[O:37])[NH:38][CH3:39])[n:8](-[c:22]4[cH:23][cH:24][c:25]([NH:28][c:29]5[cH:30][cH:31][cH:32][cH:33][c:34]5[F:35])[cH:26][cH:27]4)[n:9][c:10]3[cH:11][c:12]2[N:13]([S:14](=[O:15])(=[O:16])[CH3:17])[CH2:18][CH2:19][CH2:20][OH:21])[CH2:2][CH2:3]1.[NH2:72][c:73]1[cH:74][cH:75][c:76]([F:77])[cH:78][cH:79]1>>[CH:1]1([c:4]2[cH:5][c:6]3[c:7]([C:36](=[O:37])[NH:38][CH3:39])[n:8](-[c:22]4[cH:23][cH:24][c:25]([NH:28][c:73]5[cH:74][cH:75][c:76]([F:77])[cH:78][cH:79]5)[cH:26][cH:27]4)[n:9][c:10]3[cH:11][c:12]2[N:13]([S:14](=[O:15])(=[O:16])[CH3:17])[CH2:18][CH2:19][CH2:20][OH:21])[CH2:2][CH2:3]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-b529703f20714a23918893886c6db982
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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