p-Fluoronitrobenzene → 1,2-Diethyl-4-(4-nitrophenoxy)piperidine

HRID 232276Notes

Reaction equation

HRID 232276 reaction equation
[CH2:1]([N:3]1[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH:4]1[CH2:10][CH3:11])[CH3:2].F[C:13]1[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][CH:14]=1>>[CH2:1]([N:3]1[CH2:8][CH2:7][CH:6]([O:9][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][CH:14]=2)[CH2:5][CH:4]1[CH2:10][CH3:11])[CH3:2]

Participants

3

Reactant 2

HCID 9590p-FluoronitrobenzeneHCID 200313851,2-Diethyl-4-piperidinol

Product 1

HCID 200313581,2-Diethyl-4-(4-nitrophenoxy)piperidine

Procedure

In a manner similar to Preparation 2, react 1,2-diethyl-4-piperidinol with 4-fluoronitrobenzene to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 2

Sources & evidence

ORD record
ord-da11e3252d7546deaaa48257c9e9b210
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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