2-(difluoromethyl)-1H-1,3-benzodiazole → 1-(4-((2-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-1-yl)ethanone

HRID 2322765Notes

Reaction equation

HRID 2322765 reaction equation
[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][CH:13]1[CH2:14][CH2:15][N:16]([C:19]([CH3:20])=[O:21])[CH2:17][CH2:18]1)[n:11]2.[F:28][CH:29]([c:30]1[n:31][c:32]2[c:33]([nH:34]1)[cH:35][cH:36][cH:37][cH:38]2)[F:39]>>[c:2]1(-[n:31]2[c:30]([CH:29]([F:28])[F:39])[n:34][c:33]3[c:32]2[cH:38][cH:37][cH:36][cH:35]3)[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][CH:13]1[CH2:14][CH2:15][N:16]([C:19]([CH3:20])=[O:21])[CH2:17][CH2:18]1)[n:11]2

Participants

3

Reactant 2

HCID 5977032-(difluoromethyl)-1H-1,3-benzodiazoleHCID 584049991-(4-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-1-yl)ethanone

Product 1

HCID 533777241-(4-((2-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-1-yl)ethanone

Sources & evidence

ORD record
ord-b08e7c5abd25432ba01b87152a8d84c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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