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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2322856Generated: November 1, 2026

2-chloro-6-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-[(6-methyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)amino]thiophene-3-carboxamide

https://huagongshe.com/reaction/2322856

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-6-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-oneHCID 58216624—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-[(6-methyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)amino]thiophene-3-carboxamideHCID 44554284—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-2385d47587bf4c21b8a73a95cb8146e0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)