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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 232296Generated: October 25, 2026

1-Methyl-4-(4-nitrophenyl)piperazine → 4-(4-Methylpiperazin-1-yl)aniline

https://huagongshe.com/reaction/232296

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-4-(4-nitrophenyl)piperazineHCID 2825198—
CatalystPalladiumHCID 23938—
SolventAcetate-hydrochloric acidHCID 22641269—
Product4-(4-Methylpiperazin-1-yl)anilineHCID 737253—

Reaction Steps

In a manner similar to Preparation 3, hydrogenate 1-methyl-4-(4-nitrophenyl)piperazine over palladium on carbon in HCl/acetic acid to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04851526
Source datasetuspto-grants-1989_07
ORD IDord-3c339f88273541b28bf6deb4ad851f3d
Source noteuspto-grants-1989_07