Sodium ion → 4-{[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

HRID 2322984Notes

Reaction equation

HRID 2322984 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]1[CH2:24][CH2:25][CH:26]([CH:29]=[O:30])[CH2:27][CH2:28]1.[C:31]([O:32][BH-:33]([O:34][C:35](=[O:36])[CH3:37])[O:38][C:39](=[O:40])[CH3:41])(=[O:42])[CH3:43].[CH2:1]([CH2:2][CH3:3])[NH:4][CH:5]1[CH2:6][CH2:7][c:8]2[cH:9][cH:10][c:11]([OH:15])[cH:12][c:13]2[CH2:14]1.[Cl:45][CH:46]([Cl:47])[CH3:48].[Na+:44]>>[CH2:1]([CH2:2][CH3:3])[N:4]([CH:5]1[CH2:6][CH2:7][c:8]2[cH:9][cH:10][c:11]([OH:15])[cH:12][c:13]2[CH2:14]1)[CH2:29][CH:26]1[CH2:25][CH2:24][N:23]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:28][CH2:27]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 63651,1-DichloroethaneHCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylateHCID 2724942TriacetoxyborohydrideHCID 100587877-Propylamino-5,6,7,8-tetrahydro-naphthalen-2-ol

Product 1

HCID 686243534-{[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-e673073ab1f442c09d0359aff08bfb57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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