Ammonia → HCID 14555605, compound

HRID 232317Notes

Reaction equation

HRID 232317 reaction equation
[CH2:1]([N:6]1[CH2:11][CH2:10][N:9]([CH2:12][CH:13]2[CH2:15][CH:14]2[CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=2)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].[NH3:25].[CH2:26]=O.[CH:28]([CH:30]=O)=O>>[CH2:1]([N:6]1[CH2:11][CH2:10][N:9]([CH2:12][CH:13]2[CH2:15][CH:14]2[CH2:16][O:17][C:18]2[CH:19]=[CH:20][C:21]([N:24]3[CH:30]=[CH:28][N:25]=[CH:26]3)=[CH:22][CH:23]=2)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

5

Reactant 4

HCID 222AmmoniaHCID 712FormaldehydeHCID 7860GlyoxalHCID 20031365HCID 20031365, compound

Product 1

HCID 14555605HCID 14555605, compound

Procedure

In a manner similar to Example 1, react 4-[[2-[[4-pentylpiperazin-1-yl]methyl]cyclopropyl]methoxy]benzeneamine, aqueous ammonia, aqueous formaldehyde and aqueous glyoxal to obtain the title compound.

Sources & evidence

ORD record
ord-9badbc5881844f4a9a44ca9722b976b8
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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