Hydrazine → HCID 14555637, compound

HRID 232330Notes

Reaction equation

HRID 232330 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][N:13]2[CH2:16][CH:15]([C:17]([C:19]3[CH:24]=[CH:23][C:22]([N:25]4[CH:29]=[CH:28][N:27]=[CH:26]4)=[CH:21][CH:20]=3)=O)[CH2:14]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[OH-].[K+].NN>C(O)COCCO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][N:13]2[CH2:14][CH:15]([CH2:17][C:19]3[CH:24]=[CH:23][C:22]([N:25]4[CH:29]=[CH:28][N:27]=[CH:26]4)=[CH:21][CH:20]=3)[CH2:16]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

5

Reactant 3

HCID 9321HydrazineHCID 14797Potassium HydroxideHCID 14555636HCID 14555636, compound

Product 1

HCID 14555637HCID 14555637, compound

Reagents, catalysts & solvents 1

HCID 8117Diethylene GlycolSolvent

Procedure

In a manner similar to Example 28, react [1-[2-(3,4-dimethoxyphenyl)ethyl]azetidin-3-yl][4-(1H-imidazol-1-yl)-phenyl]methanone with potassium hydroxide and hydrazine in diethylene glycol to obtain the title compound.

Sources & evidence

ORD record
ord-ad4d33227d3a453098a7b1fc3f6a2c59
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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