Imidazole → HCID 20031304, compound

HRID 232331Notes

Reaction equation

HRID 232331 reaction equation
[CH:1]1([CH2:6][N:7]([CH2:22][CH:23]=[CH2:24])[CH:8]([CH3:21])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17](F)=[CH:16][CH:15]=2)=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:25]1[CH:29]=[CH:28][N:27]=[CH:26]1>>[CH:1]1([CH2:6][N:7]([CH2:22][CH:23]=[CH2:24])[CH:8]([CH3:21])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17]([N:25]3[CH:29]=[CH:28][N:27]=[CH:26]3)=[CH:16][CH:15]=2)=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 20031326HCID 20031326, compound

Product 1

HCID 20031304HCID 20031304, compound

Procedure

In a manner similar to Example 26, react 5-[(cyclopentylmethyl)(2-propenyl)amino]-1-(4-fluorophenyl)hexan-1-one with 1H-imidazole to obtain the title compound.

Sources & evidence

ORD record
ord-e32b97dbeb4243b2b8000603f975f091
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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