Sodium borohydride → HCID 14555639, compound

HRID 232332Notes

Reaction equation

HRID 232332 reaction equation
[CH:1]1([CH2:6][N:7]([CH2:26][CH:27]=[CH2:28])[CH:8]([CH3:25])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][N:22]=[CH:21]3)=[CH:16][CH:15]=2)=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1.[BH4-].[Na+]>>[CH:1]1([CH2:6][N:7]([CH2:26][CH:27]=[CH2:28])[CH:8]([CH3:25])[CH2:9][CH2:10][CH2:11][CH:12]([C:14]2[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][N:22]=[CH:21]3)=[CH:16][CH:15]=2)[OH:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 20031304HCID 20031304, compound

Product 1

HCID 14555639HCID 14555639, compound

Procedure

In a manner similar to Example 27, react 5-[(cyclopentylmethyl)(2-propenyl)amino]-1-[4-(1H-imidazol-1-yl)-phenyl]hexan-1-one with sodium borohydride to obtain the title compound.

Sources & evidence

ORD record
ord-d717629a8c2d4e9982dad3399e9753a4
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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