Hydrazine → HCID 14555640, compound

HRID 232333Notes

Reaction equation

HRID 232333 reaction equation
[CH:1]1([CH2:6][N:7]([CH2:26][CH:27]=[CH2:28])[CH:8]([CH3:25])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][N:22]=[CH:21]3)=[CH:16][CH:15]=2)=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-].[K+].NN>C(O)COCCO>[CH:1]1([CH2:6][N:7]([CH2:26][CH:27]=[CH2:28])[CH:8]([CH3:25])[CH2:9][CH2:10][CH2:11][CH2:12][C:14]2[CH:15]=[CH:16][C:17]([N:20]3[CH:24]=[CH:23][N:22]=[CH:21]3)=[CH:18][CH:19]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

5

Reactant 3

HCID 9321HydrazineHCID 14797Potassium HydroxideHCID 20031304HCID 20031304, compound

Product 1

HCID 14555640HCID 14555640, compound

Reagents, catalysts & solvents 1

HCID 8117Diethylene GlycolSolvent

Procedure

In a manner similar to Example 28, react 5-[(cyclopentylmethyl)(2-propenyl)amino]-1-[4-(1H-imidazol-1-yl)-phenyl]hexan-1-one with potassium hydroxide and hydrazine in diethylene glycol to obtain the title compound.

Sources & evidence

ORD record
ord-12e0099700ca481fb3b38ed7f626670d
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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