Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2323551Generated: November 3, 2026

Dichloromethane → N-Dealkylated lapatinib

https://huagongshe.com/reaction/2323551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant(5-(4-[3-Chloro-4-(3-fluoro-benzyloxy)-phenylamino]-quinazolin-6-yl)-furan-2-ylmethyl)-carbamic acid tert-butyl esterHCID 66623782—
ProductN-Dealkylated lapatinibHCID 21952026—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-35668de39ee74bbc93a2149dd5ff2bf9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)