Ammonia → HCID 53635503, compound

Participants

Reaction Steps

A solution of 0.2 g of 5'-[2-(2-acetamidophenyl)acetamido]-3'-O-acetyl-2',5'-dideoxy-5-ethyluridine in 20 ml of methanol was treated with 20 ml of methanol saturated with ammonia. The mixture was left to stand at room temperature for 17 hours. A white solid separated and was collected by filtration, washed twice with 5 ml of ethanol each time and twice with 5 ml of diethyl ether each time and subsequently dried to give 5'-[2-(2-acetamidophenyl)acetamido]-2',5'-dideoxy-5-ethyluridine of melting point 266°-267° C.

Provenance & Evidence