Sodium ion → 1-{[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]sulfonyl}-N-cyclopropyl-1H-pyrazole-4-carboxamide

HRID 2323744Notes

Reaction equation

HRID 2323744 reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[c:18]1[n:19][c:20]2[c:21]([n:22]1[CH2:23][CH:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1)[cH:30][cH:31][c:32]([S:34](=[O:35])(=[O:36])[Cl:37])[cH:33]2.[CH:3]1([NH:6][C:7](=[O:8])[c:9]2[cH:10][n:11][nH:12][cH:13]2)[CH2:4][CH2:5]1.[H-:1].[Na+:2]>>[CH:3]1([NH:6][C:7](=[O:8])[c:9]2[cH:10][n:11]([S:34]([c:32]3[cH:31][cH:30][c:21]4[c:20]([n:19][c:18]([C:14]([CH3:15])([CH3:16])[CH3:17])[n:22]4[CH2:23][CH:24]4[CH2:25][CH2:26][O:27][CH2:28][CH2:29]4)[cH:33]3)(=[O:35])=[O:36])[n:12][cH:13]2)[CH2:4][CH2:5]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 166653HydrideHCID 20785111HCID 20785111, compoundHCID 579372982-tert-Butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazole-5-sulfonyl chloride

Product 1

HCID 236601091-{[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]sulfonyl}-N-cyclopropyl-1H-pyrazole-4-carboxamide

Sources & evidence

ORD record
ord-066d3bb9cb274c57a975a43612ef8b4b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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