1,4,5,6-Tetrahydropyrimidine → 2-Chloro-5-[(5,6-dihydro-1(4H)-pyrimidinyl)methyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide

HRID 2323771Notes

Reaction equation

HRID 2323771 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([Cl:23])[c:7]([C:8](=[O:9])[NH:10][CH2:11][C:12]23[CH2:13][CH:14]4[CH2:15][CH:16]([CH2:17][CH:18]([CH2:19]2)[CH2:20]4)[CH2:21]3)[cH:22]1.[NH:24]1[CH:25]=[N:26][CH2:27][CH2:28][CH2:29]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([Cl:23])[c:7]([C:8](=[O:9])[NH:10][CH2:11][C:12]23[CH2:13][CH:14]4[CH2:15][CH:16]([CH2:17][CH:18]([CH2:19]2)[CH2:20]4)[CH2:21]3)[cH:22]1)[N:26]1[CH:25]=[N:24][CH2:29][CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 1371051,4,5,6-TetrahydropyrimidineHCID 219000205-Bromomethyl-2chloro-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide

Product 1

HCID 183815672-Chloro-5-[(5,6-dihydro-1(4H)-pyrimidinyl)methyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide

Sources & evidence

ORD record
ord-0508e456e4ac49bd8c88d9ba6f2a74f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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