Carbon tetrabromide → HCID 54325433, compound

Participants

Reaction Steps

1.26 g of 5-acetyl-2'-deoxyuridine, 1.35 g of triphenylphosphine, 1.52 g of sodium azide and 1.7 g of carbon tetrabromide in 40 ml of dimethylformamide were reacted as described in Example 54 and the product was purified by chromatography on 400 g of silica gel in dichloromethane/methanol (9:1) to give 0.80 g of 5-acetyl-5'-azido-2',5'-dideoxyuridine of melting point 159°-162° C. (decomposition).

Provenance & Evidence