Dimethyl Sulfoxide → 4-{6-Cyano-4-[4-(3-thiazol-2-ylureido)phenoxy]quinolin-7-yloxymethyl}piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][c:16]2[c:17]([C:34]#[N:35])[cH:18][c:19]3[c:20]([O:26][c:27]4[cH:28][cH:29][c:30]([NH2:33])[cH:31][cH:32]4)[cH:21][cH:22][n:23][c:24]3[cH:25]2)[CH2:12][CH2:13]1.[CH3:51][S:52]([CH3:53])=[O:54].[c:36]1([O:42][C:43](=[O:37])[NH:44][c:45]2[s:46][cH:47][cH:48][n:49]2)[cH:38][cH:39][cH:40][cH:41][cH:50]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][c:16]2[c:17]([C:34]#[N:35])[cH:18][c:19]3[c:20]([O:26][c:27]4[cH:28][cH:29][c:30]([NH:33][C:43](=[O:42])[NH:44][c:45]5[s:46][cH:47][cH:48][n:49]5)[cH:31][cH:32]4)[cH:21][cH:22][n:23][c:24]3[cH:25]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8074ab8556524f8dae2db25b476f3c43
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…