3,5-Difluoroaniline → N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3,5-difluorophenyl)-2,4-pyrimidinediamine

HRID 2324243Notes

Reaction equation

HRID 2324243 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1.[F:20][c:21]1[cH:22][c:23]([NH2:24])[cH:25][c:26]([F:28])[cH:27]1>>[c:2]1([NH:24][c:23]2[cH:22][c:21]([F:20])[cH:27][c:26]([F:28])[cH:25]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1

Participants

3

Reactant 2

HCID 965953,5-DifluoroanilineHCID 220603622-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamine

Product 1

HCID 22060977N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3,5-difluorophenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-39ad8a041775498b908006160b769299
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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