Pyridine → N-[4-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-6-methyl-pyridin-2-yl]-2-fluoro-benzenesulfonamide

HRID 2324317Notes

Reaction equation

HRID 2324317 reaction equation
[F:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[Cl:11])[cH:4][cH:5][cH:6][cH:7]1.[NH2:12][c:13]1[c:14]2[c:15]([n:16][cH:17][n:18]1)[n:19]([CH:32]([CH3:33])[CH3:34])[cH:20][c:21]2[C:22](=[O:23])[c:24]1[cH:25][c:26]([NH2:31])[n:27][c:28]([CH3:30])[cH:29]1.[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[F:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[NH:31][c:26]2[cH:25][c:24]([C:22]([c:21]3[c:14]4[c:13]([NH2:12])[n:18][cH:17][n:16][c:15]4[n:19]([CH:32]([CH3:33])[CH3:34])[cH:20]3)=[O:23])[cH:29][c:28]([CH3:30])[n:27]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 1377612-Fluorobenzenesulphonyl chlorideHCID 68902711(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(2-amino-6-methyl-pyridin-4-yl)-methanone

Product 1

HCID 68906511N-[4-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-6-methyl-pyridin-2-yl]-2-fluoro-benzenesulfonamide

Sources & evidence

ORD record
ord-ef7ac2431f8243aeb2d9cca6227436b5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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