Pyridine → Ethyl 4-methyl-2-[(methylsulfonyl)amino]-1,3-thiazole-5-carboxylate

HRID 2324340Notes

Reaction equation

HRID 2324340 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH3:12])[n:8][c:9]([NH2:11])[s:10]1.[CH3:13][S:14]([Cl:15])(=[O:16])=[O:17].[Cl:18][CH2:19][Cl:20].[cH:21]1[cH:22][cH:23][n:24][cH:25][cH:26]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH3:12])[n:8][c:9]([NH:11][S:14]([CH3:13])(=[O:16])=[O:17])[s:10]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 31297Methanesulfonyl chlorideHCID 343747Ethyl 2-amino-4-methylthiazole-5-carboxylate

Product 1

HCID 2989996Ethyl 4-methyl-2-[(methylsulfonyl)amino]-1,3-thiazole-5-carboxylate

Sources & evidence

ORD record
ord-8a80d8263aba4f36a70bd649eca9566d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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