Phosphorus tribromide → Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-4-bromobutyrate

HRID 2325298Notes

Reaction equation

HRID 2325298 reaction equation
[CH3:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8]([CH:12]([CH2:13][CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[OH:20])[cH:9][cH:10][cH:11]2)[c:21]([CH3:25])[cH:22][cH:23][cH:24]1.[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1.[P:26]([Br:27])([Br:28])[Br:29]>>[CH3:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8]([CH:12]([CH2:13][CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[Br:27])[cH:9][cH:10][cH:11]2)[c:21]([CH3:25])[cH:22][cH:23][cH:24]1

Participants

4

Reactant 3

HCID 24614Phosphorus tribromideHCID 312751,4-DioxaneHCID 21964458Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-4-hydroxy-butyrate

Product 1

HCID 21964551Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-4-bromobutyrate

Sources & evidence

ORD record
ord-4343f7a416ac47e4b36cdcb46d4a9aa3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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