Sodium ion → 5-Chloro-2-(4-methoxypyridin-3-yl)-7-morpholinothiazolo[4,5-d]pyrimidine

HRID 2325340Notes

Reaction equation

HRID 2325340 reaction equation
[CH3:19][O:20][c:21]1[c:22]([B:27]([OH:28])[OH:29])[cH:23][n:24][cH:25][cH:26]1.[CH3:36][C:37]#[N:38].[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[n:8][c:9]([I:11])[s:10]2.[Na+:30].[Na+:31].[O-:32][C:33](=[O:34])[O-:35].[OH2:18].[OH2:39]>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[n:8][c:9](-[c:22]1[c:21]([O:20][CH3:19])[cH:26][cH:25][n:24][cH:23]1)[s:10]2

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962Water2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 27625564-Methoxypyridine-3-boronic acidHCID 252527634-(5-Chloro-2-iodothiazolo[4,5-d]pyrimidin-7-yl)morpholine

Product 1

HCID 866300845-Chloro-2-(4-methoxypyridin-3-yl)-7-morpholinothiazolo[4,5-d]pyrimidine

Sources & evidence

ORD record
ord-0705480879d14a1da20b801ab3504bc6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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