Hydrazine hydrate (1:1) → 5,6-Diphenyl-4,5-dihydropyridazin-3(2h)-one

Participants

Reaction Conditions

Reaction Steps

To a mixture of 3.0 gms of the product from Step A in 25 ml of isopropyl alcohol was added 1.0 ml of hydrazine hydrate and the mixture was refluxed under nitrogen overnight. The reaction was then cooled to 0° C. and filtered and the solids were washed with water and then cold isopropyl alcohol. This afforded 2.32 g of a white solid, mp 221°-223° C.

Provenance & Evidence