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温度

0 °C

3,5-dioxo-(2H,4H)-1,2,4-triazine (48.88 g) is heated under reflux of acetic anhydride (300 ml) for 90 minutes. After cooling and concentration to dryness under vacuum, the residue is taken up in toluene (300 ml) and cooled at 0° C. for 2 hours. The white precipitate which forms is filtered off, centrifuged, and dried under vacuum at 70° C. so as to give the compound 11a (57.6 g).

1. temperatureAfter cooling
2. concentrationconcentration to dryness under vacuum
3. filtrationThe white precipitate which forms is filtered off
4. customcentrifuged, and dried under vacuum at 70° C. so as