2-Bromo-5-fluoropyridine → Acetic acid 5-(5-fluoro-pyridin-2-yl)-4-oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazin-2-ylmethyl ester
Reaction equation
[Br:16][c:17]1[n:18][cH:19][c:20]([F:23])[cH:21][cH:22]1.[F:24][c:25]1[cH:26][c:27]([F:28])[cH:29][cH:30][c:31]1[N:32]1[CH2:33][CH2:34][n:35]2[n:36][c:37]([CH2:38][O:39][c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[cH:46][c:47]2[C:48]1=[O:49].[O:1]=[C:2]1[c:3]2[n:4]([n:8][c:9]([CH2:11][O:12][C:13]([CH3:14])=[O:15])[cH:10]2)[CH2:5][CH2:6][NH:7]1>>[O:1]=[C:2]1[c:3]2[n:4]([n:8][c:9]([CH2:11][O:12][C:13]([CH3:14])=[O:15])[cH:10]2)[CH2:5][CH2:6][N:7]1[c:17]1[n:18][cH:19][c:20]([F:23])[cH:21][cH:22]1Participants
4
Sources & evidence
- ORD record
- ord-c8d3534cdbfe4ceaa9bd4a22bd9ec7d9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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