Methanol → ethyl 1-(6-(5-cyanopyrazin-2-ylamino)-4-(piperidin-3-ylmethylamino)pyridin-3-yl)-1H-pyrrole-3-carboxylate

HRID 2325717Notes

Reaction equation

HRID 2325717 reaction equation
[C:1](#[N:2])[c:3]1[n:4][cH:5][c:6]([NH:9][c:10]2[n:11][cH:12][c:13](-[n:31]3[cH:32][c:33]([C:36](=[O:37])[O:38][CH2:39][CH3:40])[cH:34][cH:35]3)[c:14]([NH:16][CH2:17][CH:18]3[CH2:19][N:20]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:21][CH2:22][CH2:23]3)[cH:15]2)[n:7][cH:8]1.[CH3:41][OH:42]>>[C:1](#[N:2])[c:3]1[n:4][cH:5][c:6]([NH:9][c:10]2[n:11][cH:12][c:13](-[n:31]3[cH:32][c:33]([C:36](=[O:37])[O:38][CH2:39][CH3:40])[cH:34][cH:35]3)[c:14]([NH:16][CH2:17][CH:18]3[CH2:19][NH:20][CH2:21][CH2:22][CH2:23]3)[cH:15]2)[n:7][cH:8]1

Participants

3

Reactant 2

HCID 887MethanolHCID 71022175tert-Butyl 3-((2-(5-cyanopyrazin-2-ylamino)-5-(3-(ethoxycarbonyl)-1H-pyrrol-1-yl)pyridin-4-ylamino)methyl)piperidine-1-carboxylate

Product 1

HCID 59613533ethyl 1-(6-(5-cyanopyrazin-2-ylamino)-4-(piperidin-3-ylmethylamino)pyridin-3-yl)-1H-pyrrole-3-carboxylate

Sources & evidence

ORD record
ord-cae1d3bebef147549d479e3d020aaac5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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