2-(Isoquinolin-5-YL)acetic acid → Methyl 4-bromo-2-(2-(isoquinolin-5-yl)acetamido)thiophene-3-carboxylate

HRID 2325838Notes

Reaction equation

HRID 2325838 reaction equation
[NH2:1][c:2]1[s:3][cH:4][c:5]([Br:11])[c:6]1[C:7](=[O:8])[O:9][CH3:10].[cH:12]1[n:13][cH:14][cH:15][c:16]2[c:17]([CH2:22][C:23](=[O:24])[OH:25])[cH:18][cH:19][cH:20][c:21]12>>[NH:1]([c:2]1[s:3][cH:4][c:5]([Br:11])[c:6]1[C:7](=[O:8])[O:9][CH3:10])[C:23]([CH2:22][c:17]1[c:16]2[cH:15][cH:14][n:13][cH:12][c:21]2[cH:20][cH:19][cH:18]1)=[O:24]

Participants

3

Reactant 2

HCID 120187082-(Isoquinolin-5-YL)acetic acidHCID 68754257Methyl 2-amino-4-bromothiophene-3-carboxylate

Product 1

HCID 59636688Methyl 4-bromo-2-(2-(isoquinolin-5-yl)acetamido)thiophene-3-carboxylate

Sources & evidence

ORD record
ord-dcbd0ce7338449e8912ee719ee600b75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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