Sodium ion → 6-chloro-4'-(3-chloro-phenyl)-2'-(3-fluoro-phenyl) spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

HRID 2325840Notes

Reaction equation

HRID 2325840 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[N:6]1[C:7](=[O:36])[C:8]2([c:9]3[cH:10][cH:11][c:12]([Cl:15])[cH:13][c:14]31)[CH:16]([c:29]1[cH:30][c:31]([F:35])[cH:32][cH:33][cH:34]1)[NH:17][C:18](=[O:28])[CH2:19][CH:20]2[c:21]1[cH:22][c:23]([Cl:27])[cH:24][cH:25][cH:26]1)[CH3:5].[Na+:38].[OH-:37]>>[NH:6]1[C:7](=[O:36])[C:8]2([c:9]3[cH:10][cH:11][c:12]([Cl:15])[cH:13][c:14]31)[CH:16]([c:29]1[cH:30][c:31]([F:35])[cH:32][cH:33][cH:34]1)[NH:17][C:18](=[O:28])[CH2:19][CH:20]2[c:21]1[cH:22][c:23]([Cl:27])[cH:24][cH:25][cH:26]1

Participants

4

Reactant 3

HCID 923Sodium ionHCID 961HydroxideHCID 765678696-Chloro-4'-(3-chlorophenyl)-2'-(3-fluorophenyl)-2,3-dihydro-2,6'-dioxo spiro[indole-3,3'-piperidine]-1-carboxylic acid ethyl ester

Product 1

HCID 866220296-chloro-4'-(3-chloro-phenyl)-2'-(3-fluoro-phenyl) spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

Sources & evidence

ORD record
ord-5077fffa12b240b0a7ced053140c070d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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