反应详情

A mixture of 0.900 gm N-benzyl-N,N'-dimethylethylenediamine, 1.10 gm powdered sodium carbonate and 0.75 ml of 2-phenylethylbromide is refluxed for 5 hours. An additional 0.25 ml of bromide is added during this time. The reaction mixture is then cooled and filtered. The filterate is concentrated in vacuo and the residue chromatographed on silica gel using an eluent of CH2Cl2 /CH3OH/NH4OH (97/3/0.3) to yield 0.875 gm of N-benzyl-N,N'-dimethyl-N'-(2-phenylethyl)ethylenediamine.

1. temperatureis refluxed for 5 hours
2. temperatureThe reaction mixture is then cooled
3. filtrationfiltered
4. concentrationThe filterate is concentrated in vacuo
5. customthe residue chromatographed on silica gel using an eluent of CH2Cl2 /CH3OH/NH4OH (97/3/0.3)