Potassium Cation → 5-[4-(3-Fluorooxetan-3-yl)phenyl]-2-({6-[(2-hydroxy-2-methylpropoxy)methyl]pyridin-2-yl}amino)thiophene-3-carboxamide
Reaction equation
[Br:21][c:22]1[cH:23][cH:24][cH:25][c:26]([CH2:28][O:29][CH2:30][C:31]([CH3:32])([OH:33])[CH3:34])[n:27]1.[C:41]([OH:42])([CH2:43][CH3:44])([CH3:45])[CH3:46].[K+:35].[K+:36].[NH2:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([C:16]3([F:20])[CH2:17][O:18][CH2:19]3)[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9].[O-:37][C:38]([O-:39])=[O:40].[O:49]=[C:50]([CH:51]=[CH:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1)[CH:59]=[CH:60][c:61]1[cH:62][cH:63][cH:64][cH:65][cH:66]1.[O:67]=[C:68]([CH:69]=[CH:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1)[CH:77]=[CH:78][c:79]1[cH:80][cH:81][cH:82][cH:83][cH:84]1.[O:85]=[C:86]([CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1)[CH:95]=[CH:96][c:97]1[cH:98][cH:99][cH:100][cH:101][cH:102]1.[Pd:47].[Pd:48]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([C:16]3([F:20])[CH2:17][O:18][CH2:19]3)[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:22]1[cH:23][cH:24][cH:25][c:26]([CH2:28][O:29][CH2:30][C:31]([CH3:32])([OH:33])[CH3:34])[n:27]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-24ed9984339b4d91a32c2edaf64d01f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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