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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2326123Generated: November 3, 2026

Hydrochloric Acid → Methyl 1-[3-(4-cyanobenzyl)-3H-imidazol-4-ylmethyl]-4-(3-methylbenzyl)piperidine-4-carboxylate

https://huagongshe.com/reaction/2326123

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoromethanesulfonic anhydrideHCID 67749—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(4-Cyanobenzyl)-5-hydroxymethyl-1H-imidazoleHCID 10198247—
ReactantMethyl 4-[(3-methylphenyl)methyl]piperidine-4-carboxylateHCID 21193292—
ProductMethyl 1-[3-(4-cyanobenzyl)-3H-imidazol-4-ylmethyl]-4-(3-methylbenzyl)piperidine-4-carboxylateHCID 15410567—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-ea218a49f9ec46a3ab88207fd6dd6bc1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)