2,4-Diamino-5-(2,3-dichlorophenyl)-6-methylpyrimidine → 2,4-Diamino-5-(2,3-dichloro-4-nitrophenyl)-6-methylpyrimidine

HRID 232615Notes

Reaction equation

HRID 232615 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1.NC1N=C(N)C(C2C=C([N+:32]([O-:34])=[O:33])C=C(Cl)C=2Cl)=C(C)N=1>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][C:12]([N+:32]([O-:34])=[O:33])=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1

Participants

3

Reactant 2

HCID 116734192,4-Diamino-5-(2,3-dichlorophenyl)-6-methylpyrimidineHCID 197051082,4-Diamino-5(2,3-dichloro-5-nitrophenyl)-6-methylpyrimidine

Product 1

HCID 197050312,4-Diamino-5-(2,3-dichloro-4-nitrophenyl)-6-methylpyrimidine

Procedure

This compound was made from the compound of Example 15 in an analogous manner to the compound of Example 3 g, mp. 265° C. Also obtained from this reaction was 2,4-diamino-5(2,3-dichloro-5-nitrophenyl)-6-methylpyrimidine.

Workup

  1. customAlso obtained from this reaction

Sources & evidence

ORD record
ord-5b72fee622bd473ba405d1c41c106c35
Source dataset
uspto-grants-1997_01
Patent number
US05591746

Reaction notes

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