Dimethyl Sulfoxide → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(9-oxooctahydro-2H-pyrazino[1,2-a]pyrazin-2-yl)-3-pyridinyl]-N,2-dimethylpropanamide
Reaction equation
[C:37]1(=[O:47])[CH:38]2[N:39]([CH2:40][CH2:41][NH:42]1)[CH2:43][CH2:44][NH:45][CH2:46]2.[C:48](=[O:49])([O-:50])[O-:51].[CH3:54][S:55]([CH3:56])=[O:57].[Cl:58][CH2:59][Cl:60].[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([CH3:17])[c:18]2[cH:19][n:20][c:21]([Cl:32])[cH:22][c:23]2-[c:24]2[c:25]([CH3:31])[cH:26][c:27]([F:30])[cH:28][cH:29]2)([CH3:33])[CH3:34])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:35])[F:36].[K+:52].[K+:53]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([CH3:17])[c:18]2[cH:19][n:20][c:21]([N:45]3[CH2:44][CH2:43][N:39]4[CH:38]([C:37](=[O:47])[NH:42][CH2:41][CH2:40]4)[CH2:46]3)[cH:22][c:23]2-[c:24]2[c:25]([CH3:31])[cH:26][c:27]([F:30])[cH:28][cH:29]2)([CH3:33])[CH3:34])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:35])[F:36]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fdd7a7448aeb41249654a4f327938f6d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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