Acetic Acid → N-{4-[(2-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}-1-methyl-1H-benzimidazol-5-yl)oxy]pyridin-2-yl}-3-(1-methylpiperidin-4-yl)propanamide
Reaction equation
[C:45]([BH3-:46])#[N:47].[CH3:41][C:42](=[O:43])[OH:44].[CH3:49][OH:50].[F:1][c:2]1[c:3]([NH:12][c:13]2[n:14][c:15]3[c:16]([n:17]2[CH3:18])[cH:19][cH:20][c:21]([O:23][c:24]2[cH:25][c:26]([NH:30][C:31]([CH2:32][CH2:33][CH:34]4[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]4)=[O:40])[n:27][cH:28][cH:29]2)[cH:22]3)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[Na+:48]>>[F:1][c:2]1[c:3]([NH:12][c:13]2[n:14][c:15]3[c:16]([n:17]2[CH3:18])[cH:19][cH:20][c:21]([O:23][c:24]2[cH:25][c:26]([NH:30][C:31]([CH2:32][CH2:33][CH:34]4[CH2:35][CH2:36][N:37]([CH3:41])[CH2:38][CH2:39]4)=[O:40])[n:27][cH:28][cH:29]2)[cH:22]3)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-49aa8510a1cc4cc8a84ab4e18ef7d6f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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