Ethyl Propionate → 2,4-Diamino-5-(2,3-dichlorophenyl)-6-ethylpyrimidine

HRID 232632Notes

Reaction equation

HRID 232632 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1.[C:18](OCC)(=O)CC>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH2:17][CH3:18])[N:3]=1

Participants

3

Reactant 2

HCID 7749Ethyl PropionateHCID 116734192,4-Diamino-5-(2,3-dichlorophenyl)-6-methylpyrimidine

Product 1

HCID 197050732,4-Diamino-5-(2,3-dichlorophenyl)-6-ethylpyrimidine

Procedure

This compound was prepared in an analogous manner to the compound of Example 15 from ethyl propionate, mp. 228°-230° C.

Sources & evidence

ORD record
ord-d8d174ea438f40d6a1000848885af4c6
Source dataset
uspto-grants-1997_01
Patent number
US05591746

Reaction notes

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