Trimethylsilyl iodide → HCID 19705063, compound

HRID 232633Notes

Reaction equation

HRID 232633 reaction equation

[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([Cl:15])[CH:12]=[C:11]([Cl:16])[C:10]=2[Cl:17])=[C:4]([CH2:18][O:19]C)[N:3]=1.C[Si](I)(C)C>S1(CCCC1)(=O)=O>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([Cl:15])[CH:12]=[C:11]([Cl:16])[C:10]=2[Cl:17])=[C:4]([CH2:18][OH:19])[N:3]=1

Participants

4

Reactant 2

HCID 85247Trimethylsilyl iodide

HCID 117391082,4-Diamino-5-(2,3,5-trichlorophenyl)-6-methoxymethylpyrimidine

Product 1

HCID 19705063HCID 19705063, compound

Reagents, catalysts & solvents 1

HCID 31347SulfolaneSolvent

Procedure

This compound was made from the compound of Example 2 by reaction with trimethylsilyl iodide in sulpholane at 80° C., mp. 101°-105° C.

Sources & evidence

ORD record: ord-dd8f6c1cd20f4b92af0a89dc65b5e779
Source dataset: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05591746

Reaction notes

Loading…