HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2326632Generated: November 1, 2026
Tris(hydroxymethyl)aminomethane → 6-methyl-N5-(3-(6-(methylamino)pyrimidin-4-yl)pyridin-2-yl)-N1(3-(trifluoromethoxy)phenyl)isoquinoline-1,5-diamine
https://huagongshe.com/reaction/2326632
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tris(hydroxymethyl)aminomethane | HCID 6503 | — |
| Reactant | Lithium ion | HCID 28486 | — |
| Reactant | 3-(Trifluoromethoxy)aniline | HCID 73753 | — |
| Reactant | 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl | HCID 2734217 | — |
| Reactant | Npc316347 | HCID 3280088 | — |
| Reactant | 1-chloro-6-methyl-N-(3-(6-(methylamino)pyrimidin-4-yl)pyridin-2-yl)isoquinolin-5-amine | HCID 58942265 | — |
| Product | 6-methyl-N5-(3-(6-(methylamino)pyrimidin-4-yl)pyridin-2-yl)-N1(3-(trifluoromethoxy)phenyl)isoquinoline-1,5-diamine | HCID 67341470 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
|---|
| ORD ID | ord-a1f7f8d44f3f4d33b143f787cc3f94b1 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
|---|
