Thionyl Chloride → HCID 21779773, compound

HRID 232668Notes

Reaction equation

[Cl:1][C:2]1[C:3]([F:14])=[C:4]([C:8]([CH3:13])=[C:9]([F:12])[C:10]=1[F:11])[C:5](O)=[O:6].S(Cl)([Cl:17])=O>>[Cl:1][C:2]1[C:3]([F:14])=[C:4]([C:8]([CH3:13])=[C:9]([F:12])[C:10]=1[F:11])[C:5]([Cl:17])=[O:6]

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 14774097HCID 14774097, compound

Product 1

HCID 21779773HCID 21779773, compound

Procedure

Employing 3-chloro-2,4,5-trifluoro-6-methylbenzoic acid (185 mg) and thionyl chloride (600 μl ), the procedure of Reference Example 18 is repeated to give 3-chloro-2,4,5-trifluoro-6-methylbenzoyl chloride (183 mg).

Sources & evidence

ORD record: ord-8663495369ed4b1da4e54289246c61f8
Source dataset: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05591744

Reaction notes

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