Cyclopropylamine → HCID 178471893, compound

HRID 232675Notes

Reaction equation

HRID 232675 reaction equation
[CH2:1]([C:3]1[C:20]([F:21])=[C:19]([F:22])[C:18]([F:23])=[C:17]([F:24])[C:4]=1[C:5]([C:7](=[CH:13]OCC)[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[O:6])[CH3:2].[CH:25]1([NH2:28])[CH2:27][CH2:26]1>>[CH2:1]([C:3]1[C:20]([F:21])=[C:19]([F:22])[C:18]([F:23])=[C:17]([F:24])[C:4]=1[C:5]([C:7](=[CH:13][NH:28][CH:25]1[CH2:27][CH2:26]1)[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[O:6])[CH3:2]

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 54246622Ethyl 2-(2-ethyl-3,4,5,6-tetrafluorobenzoyl)-3-ethoxyacrylate

Product 1

HCID 178471893HCID 178471893, compound

Procedure

Employing ethyl 2-(2-ethyl-3,4,5,6-tetrafluorobenzoyl)-3-ethoxyacrylate and cyclopropylamine, the procedure of Reference Example 21 is repeated to give ethyl 2-(2-ethyl-3,4,5,6-tetrafluorobenzoyl)-3-cyclopropylaminoacrylate.

Sources & evidence

ORD record
ord-cd20823c18384d119f79e05626ae6d2c
Source dataset
uspto-grants-1997_01
Patent number
US05591744

Reaction notes

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