HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2326844Generated: November 2, 2026
Water → Ethyl 1-cyclopropyl-7-[5-(2,4-diamino-pyrimidin-5-ylmethyl)-2,3-dimethoxy-phenylethynyl]-6,8-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate
https://huagongshe.com/reaction/2326844
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Cyclopropyl-7-trifluoromethylsulfonyloxy-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester | HCID 15636880 | — |
| Reactant | 5-[3-Ethynyl-4,5-dimethoxy-benzyl]-pyrimidine-2,4-diamine | HCID 17890950 | — |
| Product | Ethyl 1-cyclopropyl-7-[5-(2,4-diamino-pyrimidin-5-ylmethyl)-2,3-dimethoxy-phenylethynyl]-6,8-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate | HCID 19081771 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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| ORD ID | ord-1a9dd11d4c1645ee84b2f00782fb4bfa |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
|---|
