3-(3-Methylphenyl)acrylic acid → N-[1-[[5-(1,1-difluoroethyl)furan-2-yl]methyl]pyrazol-3-yl]-3-(3-methylphenyl)prop-2-enamide
Reaction equation
[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][c:13]([NH2:16])[cH:14][cH:15]2)[o:9]1.[c:17]1([CH3:28])[cH:18][c:19]([CH:23]=[CH:24][C:25](=[O:26])[OH:27])[cH:20][cH:21][cH:22]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][c:13]([NH:16][C:25]([CH:24]=[CH:23][c:19]3[cH:18][c:17]([CH3:28])[cH:22][cH:21][cH:20]3)=[O:26])[cH:14][cH:15]2)[o:9]1Participants
3
Sources & evidence
- ORD record
- ord-e8788af47e4245d7a7f81d0ff02109a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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