Triethyl phosphonoacetate → Ethyl 3-(5-{4-[4-(3-fluorobenzyloxy)-3-chloroanilino]-6-quinazolinyl}-2-furyl)-2-propenoate
Reaction equation
[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH2:40][P:41]([O:42][CH2:43][CH3:44])([O:45][CH2:46][CH3:47])=[O:48].[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][cH:12][c:13](-[c:16]4[cH:17][cH:18][c:19]([CH:21]=[O:22])[o:20]4)[cH:14][c:15]23)[cH:23][cH:24][c:25]1[O:26][CH2:27][c:28]1[cH:29][c:30]([F:34])[cH:31][cH:32][cH:33]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][cH:12][c:13](-[c:16]4[cH:17][cH:18][c:19]([CH:21]=[CH:40][C:38]([O:37][CH2:36][CH3:35])=[O:39])[o:20]4)[cH:14][c:15]23)[cH:23][cH:24][c:25]1[O:26][CH2:27][c:28]1[cH:29][c:30]([F:34])[cH:31][cH:32][cH:33]1Participants
3
Sources & evidence
- ORD record
- ord-2f163a384220448d8951f27790cb676c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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