Methanol → [2-(2-{3-Amino-2-[bis-(4-methoxybenzyl)amino]-6-chloro-5-methylpyridin-4-ylamino}ethoxy)ethyl]carbamic acid tert-butyl ester
Reaction equation
[BH4-:1].[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8]([NH:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][NH:15][c:16]1[c:17]([N+:43]([O-:44])=[O:45])[c:18]([N:24]([CH2:25][c:26]2[cH:27][cH:28][c:29]([O:32][CH3:33])[cH:30][cH:31]2)[CH2:34][c:35]2[cH:36][cH:37][c:38]([O:41][CH3:42])[cH:39][cH:40]2)[n:19][c:20]([Cl:23])[c:21]1[CH3:22])=[O:46].[CH3:47][OH:48].[Cl:49][CH2:50][Cl:51].[Na+:2].[Ni:53]([Cl:54])[Cl:55].[OH2:52]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8]([NH:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][NH:15][c:16]1[c:17]([NH2:43])[c:18]([N:24]([CH2:25][c:26]2[cH:27][cH:28][c:29]([O:32][CH3:33])[cH:30][cH:31]2)[CH2:34][c:35]2[cH:36][cH:37][c:38]([O:41][CH3:42])[cH:39][cH:40]2)[n:19][c:20]([Cl:23])[c:21]1[CH3:22])=[O:46]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-eade2448d0924a98b6910e73d9f7d87f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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