Chloroacetyl chloride → HCID 10912429, compound

HRID 232708Notes

Reaction equation

[Cl:1][CH2:2][C:3](Cl)=[O:4].[CH:6]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:18]=1[NH:17][C:16](=[O:19])[CH2:15][CH2:14]2)([CH3:8])[CH3:7]>>[Cl:1][CH2:2][C:3]([C:11]1[CH:12]=[C:13]2[C:18](=[C:9]([CH:6]([CH3:7])[CH3:8])[CH:10]=1)[NH:17][C:16](=[O:19])[CH2:15][CH2:14]2)=[O:4]

Participants

Reactant 2

HCID 6577Chloroacetyl chloride

HCID 10877924HCID 10877924, compound

Product 1

HCID 10912429HCID 10912429, compound

Procedure

By using chloroacetyl chloride and 8-isopropyl-3,4-dihydrocarbostyril, there was obtained 6-chloroacetyl-8-isopropyl-3,4-dihydrocarbostyril as a white powder having a melting point of 224°-229° C.

Sources & evidence

ORD record: ord-52982b4a8fd547ce9896515c869b7797
Source dataset: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05591751

Reaction notes

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