Acetone → 6-bromo-4-(hydroxymethyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
Reaction equation
[BH4-:31].[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:27]1)[C:7]([CH:21]=[CH2:22])([C:23]([F:24])([F:25])[F:26])[O:8][C:9](=[O:20])[N:10]2[CH2:11][c:12]1[cH:13][cH:14][c:15]([O:18][CH3:19])[cH:16][cH:17]1.[CH3:33][C:34](=[O:35])[CH3:36].[CH3:40][OH:41].[Cl:37][CH2:38][Cl:39].[Na+:32].[O-:28][O+:29]=[O:30]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:27]1)[C:7]([CH2:21][OH:28])([C:23]([F:24])([F:25])[F:26])[O:8][C:9](=[O:20])[N:10]2[CH2:11][c:12]1[cH:13][cH:14][c:15]([O:18][CH3:19])[cH:16][cH:17]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-63f1ec8da39c4610a55bff55c218f9e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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