Dimethyl Sulfoxide → 4-Amino-6-(2-fluoro-4-nitrophenoxy)pyrimidine

HRID 2327315Notes

Reaction equation

HRID 2327315 reaction equation
[CH3:24][S:25](=[O:26])[CH3:27].[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[F:1][c:2]1[c:3]([OH:11])[cH:4][cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[H-:12].[NH2:14][c:15]1[n:16][cH:17][n:18][c:19]([Cl:21])[cH:20]1.[Na+:13].[Na+:23].[OH-:22]>>[F:1][c:2]1[c:3]([O:11][c:19]2[n:18][cH:17][n:16][c:15]([NH2:14])[cH:20]2)[cH:4][cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 923Sodium ion2×HCID 961HydroxideHCID 3283Diethyl EtherHCID 98252-Fluoro-4-nitrophenolHCID 166653HydrideHCID 2380124-Amino-6-chloropyrimidine

Product 1

HCID 231530124-Amino-6-(2-fluoro-4-nitrophenoxy)pyrimidine

Sources & evidence

ORD record
ord-5bc0b93771ac497ca839f0e5dafd3bac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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