5-Methoxycarbonyl-2-thiophenecarboxylic acid hydrazide → methyl 5-{[2-(1-{4-hydroxy-1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}ethylidene)hydrazino]carbonyl}-2-thiophenecarboxylate

HRID 2327363Notes

Reaction equation

HRID 2327363 reaction equation
[NH:21]([NH2:22])[C:23](=[O:24])[c:25]1[cH:26][cH:27][c:28]([C:30](=[O:31])[O:32][CH3:33])[s:29]1.[OH:1][c:2]1[c:3]([C:18]([CH3:19])=[O:20])[n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1>>[OH:1][c:2]1[c:3]([C:18]([CH3:19])=[N:22][NH:21][C:23](=[O:24])[c:25]2[cH:26][cH:27][c:28]([C:30](=[O:31])[O:32][CH3:33])[s:29]2)[n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1

Participants

3

Reactant 2

HCID 148719615-Methoxycarbonyl-2-thiophenecarboxylic acid hydrazideHCID 602067901-[4-hydroxy-1-methyl-5-(4-trifluoromethylphenyl)-1H-pyrazol-3-yl]ethanone

Product 1

HCID 72360041methyl 5-{[2-(1-{4-hydroxy-1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}ethylidene)hydrazino]carbonyl}-2-thiophenecarboxylate

Sources & evidence

ORD record
ord-1679d37c6c5c49bf815af6ad8381964a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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