反应详情

N-(4-Bromo-3-methyl-5-isoxazolyl)-2,5-dimethylthiophene-3-sulfonamide was prepared in the same manner as described in Example 1 from 5-amino-4-bromo-3-methylisoxazole and 2,5-dimethylthiophene-3-sulphonyl chloride in 55% yield. Purification was achieved by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 77°-80° C.

1. customPurification
2. customwas achieved by recrystallization from ethyl acetate/hexanes
3. customto give a crystalline solid, m.p. 77°-80° C.